Pan Pathogen NGS Assay

Overview


Infectious diseases claim over 17 million lives annually, posing a severe threat to global health. Rapid and accurate pathogen detection is critical for effective treatment and prevention. Conventional tools like real-time PCR and antibody-based assays detect only a few pathogens at a time, often with low sensitivity and risk of false negatives. While PCR can identify pathogens during outbreaks, it lacks sequence-level data, making it impossible to trace transmission pathways or cluster cases accurately. High-resolution whole-genome sequencing of pathogens from vectors and reservoirs unlocks insights into epidemiology and evolution. Yet, traditional NGS approaches struggle with low pathogen-to-host DNA ratios. Our advanced solutions overcome these challenges, delivering high-quality pathogen sequence data for precision diagnostics and research.

Genes2Me Pan Pathogen Assay leverages targeted next-generation sequencing (tNGS) with advanced hybridization capture technology to enrich pathogen-specific genes from complex samples. Powered by a clinical-grade reference database, patented innovations, and intelligent bioinformatics algorithms, this solution detects pathogens (viruses, bacteria, fungi, parasites and other pathogenic microorganisms), drug-resistance genes, and virulence markers with unmatched accuracy. Designed to support precise diagnosis and targeted treatment, the panel enables clinicians to identify infections, assess resistance profiles, and guide effective therapeutic decisions all in one streamlined workflow.

Product key features & benefits


  • Ultra Broad Spectrum: One test covers more than 95% of common clinical pathogen infections.
  • Comprehensive Pathogen Detection: Identifies viruses, bacteria, fungi, parasites, and other pathogenic microorganisms in a single test.
  • High Sensitivity and Speed: Delivers accurate detection of trace pathogens using high-throughput targeted sequencing with no host DNA interference and provides rapid identification of critical infections within just 16 hours.
  • High-Precision Technology: Utilizes hybridization-based enrichment and second-generation high-throughput sequencing for accurate detection of trace microbial nucleic acids.
  • Multi-Drug Resistance Profiling: Detects multiple resistance genes to guide effective antimicrobial therapy.

Panel Specifications


Parameter Description
Number of Organism 7000+
Target Size ~8000 probes
Target Regions 16S and internal transcribed spacer (ITS)
Input Sample type Blood, Sputum, Saliva, Stool, Swab, Fresh tissue, Body fluid
Genes Housekeeping genes, drug-resistant related genes
Data Required 3-5 million reads, ~1 GB data
Recommended sequencers Illumina, MGI, Element Biosciences (AVITI)

Process Workflow


Pan Pathogen-work-flow

Ordering Information


Commercial Name Cat No. Pack Size Platform
LeoNext PanPathogen NGS Test Kit G710021-1 24 T Illumina
G710021-2 96 T Illumina
G710021-3 96 T - EZY Illumina – EZY
LeoNext PanPathogen NGS Test Kit G710021-4 24 T MGI
G710021-5 96 T MGI
G710021-6 96 T – EZY MGI – EZY
LeoNext PanPathogen NGS Test Kit G710021-7 24 T Aviti
G710021-8 96 T Aviti
G710021-9 96 T – EZY Aviti – EZY
LeoNext PanPathogen NGS Test Kit G710021-10 24 T Thermo
G710021-11 96 T Thermo
G710021-12 96 T – EZY Thermo – EZY

Resources


Download useful documents and technical information for the PanPathogen NGS Test Kit

Product Enquiry Form


Since its inception in 2016, Genes2me has been constantly striving towards setting a benchmark in the diagnostics space by introducing premium quality (Made in India) diagnostic kits which are CE-IVD, ISO-13485:2016, and ISO 9001:2015 certified, assuring our clients of unparalleled quality and compliance with international standards.

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