Zika virus (ZIKV), a member of the Flavivirus genus, is primarily transmitted by Aedes aegypti and Aedes albopictus mosquitoes. Since its discovery in 1947, Zika has emerged as a major global health concern due to its capacity to spread rapidly and cause severe complications. While most infections present with mild fever, rash, joint pain, and conjunctivitis, Zika is particularly dangerous because of its association with neurological complications such as Guillain-Barré syndrome, and with serious birth defects including microcephaly in newborns when infection occurs during pregnancy. Given the overlap in symptoms with Dengue and other arboviral infections, accurate molecular diagnosis is essential for timely patient management and outbreak control.
The ZikaQ Real-Time PCR Kit from Genes2Me is a highly sensitive and specific in vitro diagnostic solution designed for the qualitative detection of Zika virus RNA across a broad range of clinical sample types, including blood, serum, plasma, urine, and saliva. By combining molecular precision with workflow efficiency, the kit strengthens outbreak preparedness and supports better patient outcomes.
Genes2Me is a CE Marked molecular diagnostics company trusted by clinical laboratories across global markets. The ZikaQ Real-Time PCR Kit meets European conformity standards for in vitro diagnostic devices, validated to international benchmarks for accuracy, reliability, and safety.
The ZikaQ Kit is based on real-time reverse transcription PCR (RT-PCR), targeting the Poly gene region of the ZIKV genome for precise detection. Fluorescently labeled probes detect ZIKV RNA in the HEX channel, while an Internal Control based on a human housekeeping gene is monitored in the Cy5 channel to validate the complete process from extraction through amplification. This design eliminates false negatives arising from poor sample quality or PCR inhibition and enhances overall result reliability. Ready-to-use reagents and a straightforward protocol minimise hands-on time and reduce the potential for procedural errors.
Zika virus infection is frequently asymptomatic or presents with non-specific febrile illness, making clinical diagnosis unreliable. Serological testing is further complicated by cross-reactivity with related flaviviruses such as Dengue, Yellow Fever, and West Nile virus. Molecular detection of ZIKV RNA provides the earliest confirmation of active infection, ahead of antibody seroconversion, and is the recommended approach during the acute viremic phase. The broad sample type compatibility of the ZikaQ kit—spanning blood, serum, plasma, urine, and saliva—is especially important given that ZIKV RNA persists in urine and saliva beyond the period of detectable viraemia, extending the diagnostic window for timely confirmation.
Detects ZIKV RNA with a Ct cut-off of 35 or below, ensuring accurate diagnosis even at low viral loads and during early or subclinical infection.
A human housekeeping gene monitored in the Cy5 channel validates the complete workflow from sample extraction through amplification, ensuring result reliability and eliminating false negatives.
No false positives observed with closely related flaviviruses including Dengue, Yellow Fever, and West Nile virus, confirming high assay specificity in clinically relevant differential diagnosis scenarios.
Validated across blood, serum, plasma, urine, and saliva, extending the diagnostic window beyond the acute viremic phase and supporting testing across diverse clinical presentations.
Results available significantly faster than conventional serological methods, enabling clinicians to initiate timely and targeted patient management decisions.
Validated on RapiCycler 96, Bio-Rad CFX96, QuantStudio 5, and LightCycler 480, supporting seamless integration into existing laboratory workflows.
| Commercial Name | Old Cat No. | New Cat No. | Pack Size |
|---|---|---|---|
| ZikaQ Real-Time PCR Kit | G2M262621 | 50 Tests |
Since its inception in 2016, Genes2me has been constantly striving towards setting a benchmark in the diagnostics space by introducing premium quality (Made in India) diagnostic kits which are CE-IVD, ISO-13485:2016, and ISO 9001:2015 certified, assuring our clients of unparalleled quality and compliance with international standards.
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