Human Herpesviruses (HHVs) are a family of DNA viruses capable of establishing lifelong latent infections in humans. Among them, HHV-6 and HHV-7 are commonly associated with roseola infantum and febrile illnesses, while HHV-8, also known as Kaposi’s Sarcoma-Associated Herpesvirus (KSHV), is linked to Kaposi’s Sarcoma, Primary Effusion Lymphoma, and Multicentric Castleman Disease. These viruses can remain dormant for years and reactivate during periods of immune suppression, leading to significant clinical complications.
The HHV-Q Real-Time PCR Kit from Genes2Me is a highly sensitive and specific in vitro diagnostic assay for the qualitative detection of HHV-6, HHV-7, and HHV-8 DNA in a wide range of clinical specimens. By combining precise molecular targeting with robust quality controls, the kit enables rapid identification of active HHV infections and supports timely clinical decision-making for high-risk patient populations.
The HHV-Q kit is a CE-IVD marked assay built on real-time PCR technology with primers and probes specifically designed to detect HHV-6, HHV-7, and HHV-8 DNA. The assay utilizes a three-tube format for independent detection of each viral target. Target amplification is detected through virus-specific fluorescent channels, while an Exogenous Internal Control monitored in the HEX channel validates extraction quality and PCR efficiency in every run.
Positive and negative controls are included to ensure workflow reliability and minimize the risk of false-positive or false-negative results. Ready-to-use reagents and a streamlined workflow help reduce hands-on time and improve laboratory efficiency.
HHV infections often present with non-specific clinical symptoms and may remain latent for prolonged periods before reactivation. In immunocompromised patients, transplant recipients, and oncology patients, reactivation can result in serious complications requiring rapid clinical intervention.
Conventional diagnostic methods may not provide the speed or sensitivity required for effective patient management. Molecular detection of HHV DNA offers direct evidence of infection, enabling earlier diagnosis, improved monitoring, and more informed treatment decisions. Real-time PCR provides a highly sensitive and specific approach for identifying HHV infections, particularly in patients where rapid diagnosis is critical.
Simultaneously supports detection of HHV-6, HHV-7, and HHV-8 using a standardized molecular workflow.
The HEX-channel Exogenous Internal Control validates nucleic acid extraction and PCR efficiency, reducing the risk of false-negative results.
Ensures assay integrity and reliable result interpretation in every run.
Validated for use with blood, serum, plasma, CSF, saliva, swabs, tissue biopsies, and lymph node aspirates.
Ct cut-off of 35 or below enables reliable detection of HHV DNA, even at low concentrations.
Provides faster and more sensitive detection compared with conventional laboratory methods.
Simplifies laboratory workflow while supporting long-term inventory management.
Validated on RapiCycler 96, Bio-Rad CFX96, QuantStudio 5, and LightCycler 480 systems.
HHV-Q Real Time PCR specific amplification plot of HHV-6 Positive Control (FAM Channel), HHV-7 Positive Control (Cy5 Channel) & HHV-8 Positive Control (FAM Channel) along with Exogenous Internal Control (HEX Channel)
| Commercial Name | Old Cat No. | New Cat No. | Pack Size |
|---|---|---|---|
| HHV-Q Real-Time PCR Kit | G2M802421 | 50 Tests |
Since its inception in 2016, Genes2me has been constantly striving towards setting a benchmark in the diagnostics space by introducing premium quality (Made in India) diagnostic kits which are CE-IVD, ISO-13485:2016, and ISO 9001:2015 certified, assuring our clients of unparalleled quality and compliance with international standards.
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