Overview

The SpiNXT Blood DNA Extraction Kit is designed for efficient isolation and purification of high-quality genomic DNA from human blood-derived samples including whole blood, plasma, serum, buffy coat, and isolated lymphocytes. The kit is compatible with blood collected in EDTA, citrate, and heparin anticoagulant tubes, ensuring flexibility across routine and archived samples. The optimized lysis chemistry enables effective disruption of blood cells and complete protein digestion, while efficiently removing common blood-derived inhibitors such as heme, anticoagulants, and enzymatic contaminants. The formulation is specifically suited for heparin-treated blood samples, overcoming PCR inhibition commonly associated with heparin and enabling reliable downstream molecular analysis. During purification, genomic DNA is selectively retained while proteins, salts, residual anticoagulants, and other impurities are removed through sequential wash steps. Purified DNA is eluted in a low-salt buffer, resulting in high-purity, intact DNA suitable for sensitive molecular biology applications.