Identify Significant Somatic Mutations in Solid Tumors
The OncoFOCUS Panel v3.0 covers 250+ actionable mutations in 5 key oncogenes observed in lung, colorectal, and metastatic tumors including EGFR, KRAS, NRAS, and BRAF.
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Profiling over 200+ significant somatic mutations in 5 key oncogenes.
Able to detect and quantify mutation frequencies as low as 5%.
Can utilise a minimal 20ng input DNA.
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| GENE | COVERAGE | MUTATION |
| BRAF | Substitutions and deletions in codon 469 of exon 11; codons 594, 597, 600,601 of exon 15 | 25 |
| EGFR | Substitutions, insertions, and deletions across exons 18, 19, 20, and 21. Includes key mutations such as L858R, L861Q, and T790M | 125 |
| KIT | Substitution mutations in exons 11, 13, and 17 | 6 |
| KRAS | Substitution mutations across codons 12, 13 of exon 2; codons 59, 61 of exon 3; codons 117, 146 of exon 4 | 43 |
| NRAS | Substitution mutations across codons 12, 13 of exon 2; codons 59, 61 of exon 3; codons 117, 146 of exon 4 | 31 |
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Accurate Reporting
Fast TAT
Stringent QC
