UltraCHECK Colon Panel v2.0

Ultra-Sensitive mutation screening test for Colorectal Cancer via a Simple Blood Draw

The UltraCHECK Colon Panel v2.0 enables mutation detection in liquid biopsy samples as low as 0.1% allele frequency. This targeted highly sensitive panel identify mutations across heterogeneous tumor samples, circulating cell-free DNA (ctDNA) or circulating tumor cells (CTCs), responsible for colorectal cancer.

What it screen?

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Gene	Coverage	Mutations
BRAF	Codon 469 of exon 11; codons 594, 600 of exon 15	5
EGFR	Extracellular domain mutations across exon 12	10
KRAS	Codons 12, 13 of exon 2; codons 59, 61 of exon 3; codons 117, 146 of exon 4	48
NRAS	Codons 12, 13 of exon 2; codons 59, 61 of exon 3; codons 117, 146 of exon 4	40
PIK3CA	Codons 542, 545 of exon 9; codon 1047 of exon 20	4