mRNA
Sequencing
This assay specifically targets messenger RNA (mRNA) — the RNA that is translated into protein — primarily covering protein-coding genes. It is suited to studies of gene expression levels and changes in protein-coding genes across conditions, providing a detailed profile of overall messenger rna structure, including quantification of transcript levels and alternative splicing events specific to coding genes.
Explore mRNA →Prep Kit
Applications in Clinical & Research
Comprehensive genome-wide insights for complex biological questions.
Quantification of coding-gene expression levels.
Detection of alternative splicing events in protein-coding genes.
Determining the role of mRNA in protein synthesis.
Patient stratification in clinical environments and clinical trials (e.g., tumor marker expression profiling).
Characterization of cell composition / heterogeneity in complex tissues.
Improved diagnostic rates in suspected Mendelian conditions by prioritizing candidate variants from exome/genome sequencing.
Discovery of novel mutations or expression changes in undiagnosed/rare genetic disorders.
Variations
Indels
Variants
Key Features
Fast & Efficient
Optimized workflow for consistent results.
High Performance Chemistry
Reliable and reproducible library preparation.
Low Input
Works with as little as 100 pg of DNA.
Wide Sample Compatibility
Supports multiple sample types and challenging samples.
Comprehensive Coverage
Detects SNVs, Indels, CNVs and SVs.
Multi-Platform Support
Illumina, Thermo Fisher, MGI and Element Biosciences.
Parameter & Specifications
| Parameter | Detail |
|---|---|
| Methodology | mRNA enrichment (Poly A selection) |
| Technology | Next Generation Sequencing |
| Assay time | ~8 hrs |
| Biomarker | Fusion and variants |
| Instrument compatibility | Illumina, MGI, ThermoFisher & Element Biosciences (Aviti) |
| Specification | Detail |
|---|---|
| Methodology | mRNA enrichment (Poly A selection) |
| RNA Input Quantity | 1 µg |
| Sample Types | Blood, Saliva, Fresh tissue |
| Biomarker | Fusion and variants |
| Platform Compatibility | Illumina, MGI, ThermoFisher, Element Biosciences (Aviti) |
High-quality data for confident results
Experience superior coverage, accurate variant detection and reliable performance across a wide range of sample types and applications. The WGS solution delivers clean, consistent data to support research and genomic investigations.
& Uniformity
Detection
Reproducible
Streamlined Library Preparation Workflow
A simplified path from genomic material to sequencing data.
Extraction
High-quality genomic DNA from your samples.
Library Preparation
Optimized chemistry for maximum efficiency.
Sequencing
High-throughput platform compatibility.
Analysis
Reliable data for meaningful genomic insights.
Explore the complete genome.
Unlock broader genomic insights with a streamlined library preparation workflow.